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Molecular cloning of the human hepatitis C virus genome from Japanese patients with non-A, non-B hepatitis.

1 Dec 1990

Abstract excerpt

The nucleotide sequence of the Japanese type of hepatitis C virus (HCV-J) genome, consisting of 9413 nucleotides, was determined by analyses of cDNA clones from plasma specimens from Japanese patients with chronic hepatitis. HCV-J genome contains a long open reading frame that can encode a sequence of 3010 amino acid residues. Comparison of HCV-J with the American isolate of HCV showed 22.6% difference in...

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PMID: 2175903
DOI: 10.1073/pnas.87.24.9524

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