Article
The role of replication initiation control in promoting survival of replication fork damage.
Molecular microbiology - 1 Apr 2006
Sutera Vincent A, Lovett Susan T
Abstract excerpt
Dam methylase mutants were recovered in a screen for mutants sensitive to UV irradiation or mild inhibition of replication elongation. Dam's role in tolerance of DNA damage is to provide binding sites for SeqA, because seqA mutants showed similar sensitivity that was genetically epistatic to dam. The sensitivity of seqA mutants to UV irradiation and to the replication inhibitors hydroxyurea (HU) and...
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