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Article

Disruption of axo-glial junctions causes cytoskeletal disorganization and degeneration of Purkinje neuron axons.

Proceedings of the National Academy of Sciences of the United States of America - 28 Mar 2006

Garcia-Fresco German P, Sousa Aurea D, Pillai Anilkumar M, Moy Sheryl S, Crawley Jacqueline N, Tessarollo Lino, Dupree Jeffrey L, Bhat Manzoor A

Abstract excerpt

Axo-glial junctions (AGJs) play a critical role in the organization and maintenance of molecular domains in myelinated axons. Neurexin IV/Caspr1/paranodin (NCP1) is an important player in the formation of AGJs because it recruits a paranodal complex implicated in the tethering of glial proteins to the axonal membrane and cytoskeleton. Mice deficient in either the axonal protein NCP1 or the glial ceramide...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 16551741
DOI: 10.1073/pnas.0601082103
PMCID: PMC1405910

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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