Article
Nervous system defects of AnkyrinB (-/-) mice suggest functional overlap between the cell adhesion molecule L1 and 440-kD AnkyrinB in premyelinated axons.
The Journal of cell biology - 30 Nov 1998
Scotland P, Zhou D, Benveniste H, Bennett V
Abstract excerpt
The L1 CAM family of cell adhesion molecules and the ankyrin family of spectrin-binding proteins are candidates to collaborate in transcellular complexes used in diverse contexts in nervous systems of vertebrates and invertebrates. This report presents evidence for functional coupling between L1...
Topics
- Animals
- Ankyrins
- Axons
- Brain
- Female
- Humans
- Leukocyte L1 Antigen Complex
- Male
- Membrane Glycoproteins
- Mice
- Mice, Inbred C57BL
- Mice, Knockout
- Mutation
- Nerve Degeneration
- Nervous System Malformations
- Neural Cell Adhesion Molecules
- Optic Nerve
- Phenotype