Article
Protein 4.1B contributes to the organization of peripheral myelinated axons.
PloS one - 1 Jan 2011
Cifuentes-Diaz Carmen, Chareyre Fabrice, Garcia Marta, Devaux Jérôme, Carnaud Michèle, Levasseur Grégoire, Niwa-Kawakita Michiko, Harroch Sheila, Girault Jean-Antoine, Giovannini Marco, Goutebroze Laurence
Abstract excerpt
Neurons are characterized by extremely long axons. This exceptional cell shape is likely to depend on multiple factors including interactions between the cytoskeleton and membrane proteins. In many cell types, members of the protein 4.1 family play an important role in tethering the cortical actin-spectrin cytoskeleton to the plasma membrane. Protein 4.1B is localized in myelinated axons, enriched in paranodal...
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