CSF Abeta42, Tau and phosphorylated Tau, APOE epsilon4 allele and MCI type in progressive MCI.

doi:10.1016/j.neurobiolaging.2006.02.001

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Article

CSF Abeta42, Tau and phosphorylated Tau, APOE epsilon4 allele and MCI type in progressive MCI.

Neurobiology of aging - 1 Apr 2007

Herukka Sanna-Kaisa, Helisalmi Seppo, Hallikainen Merja, Tervo Susanna, Soininen Hilkka, Pirttilä Tuula

Abstract excerpt

BACKGROUND: The patients with mild cognitive impairment (MCI) have an elevated risk for Alzheimer's disease (AD). Especially the amnestic MCI is seen as prodrome of AD. Apolipoprotein E (APOE) epsilon4 allele, abnormal CSF Abeta42, Tau and phosphorylated Tau (phospho-Tau) levels are associated with elevated risk for AD. METHODS: APOE genotyping was done by PCR based method and baseline CSF Abeta42, Tau and...

Topics

Aged
Alleles
Amyloid beta-Peptides
Analysis of Variance
Apolipoprotein E4
Cognition Disorders
Dementia
Disease Progression
Enzyme-Linked Immunosorbent Assay
Female
Humans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Male

Peptide Fragments

Phosphorylation

Predictive Value of Tests

Survival Analysis

tau Proteins

Source

Open in PubMed

Identifiers

PMID: 16546302
DOI: 10.1016/j.neurobiolaging.2006.02.001

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-16546302-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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