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Article

Effects of apolipoprotein E-epsilon4 and -epsilon2 in amnestic mild cognitive impairment and dementia in Shanghai: SCOBHI-P.

American journal of Alzheimer's disease and other dementias - 1 May 2010

Borenstein Amy R, Mortimer James A, Ding Ding, Schellenberg Gerard D, DeCarli Charles, Qianhua Zhao, Copenhaver Cathleen, Qihao Guo, Shugang Chu, Galasko Douglas, Salmon David P, Qi Dai, Yougui Wu, Petersen Ronald, Zhen Hong

Abstract excerpt

OBJECTIVE: To determine apolipoprotein E (APOE)-epsilon4 and -epsilon2 frequencies and risk of mild cognitive impairment (MCI) and dementia in Shanghai, China. METHODS: A total of 34 MCI and 34 dementia cases were recruited from an urban Memory Disorders Clinic and 32 controls were recruited from a residential community served by the clinic. Apolipoprotein E was genotyped using standard methods. RESULTS: Among...

Topics

Aged
Amnesia
Apolipoprotein E2
Apolipoprotein E4
Catchment Area, Health
China
Cognition Disorders
Dementia
Female
Genotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Humans

Male

Neuropsychological Tests

Severity of Illness Index

Source

Open in PubMed Open full text

Identifiers

PMID: 20142627
DOI: 10.1177/1533317509357736
PMCID: PMC2872993

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-20142627-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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