Lessons from IgA Nephropathy Models

doi:10.3390/ijms252111484

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Lessons from IgA Nephropathy Models

25 Oct 2024

Abstract excerpt

IgA nephropathy (IgAN) is the most common type of primary glomerulonephritis worldwide; however, the underlying mechanisms of this disease are not fully understood. This review explores several animal models that provide insights into IgAN pathogenesis, emphasizing the roles of aberrant IgA1 glycosylation and immune complex formation. It discusses spontaneous, immunization, and transgenic models illustrating...

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PMID: 39519036
DOI: 10.3390/ijms252111484

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