Article
Caveolin-1 expression is associated with a basal-like phenotype in sporadic and hereditary breast cancer.
Breast cancer research and treatment - 1 Sept 2006
Pinilla Socorro María Rodríguez, Honrado Emiliano, Hardisson David, Benítez Javier, Palacios José
Abstract excerpt
The role of caveolin 1 (CAV1), a structural component of caveolae in breast cancer is controversial, although most studies suggest that it functions as a tumor-suppressor gene. In addition, some studies have identified CAV1 as a marker of myoepithelial cells. Since myoepithelial markers are frequently expressed in breast carcinomas with a basal-like phenotype, which are frequently occurring tumors in women with...
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