Article
Prognostic significance of basal-like phenotype and fascin expression in node-negative invasive breast carcinomas.
Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Mar 2006
Rodríguez-Pinilla Socorro María, Sarrió David, Honrado Emiliano, Hardisson David, Calero Francisco, Benitez Javier, Palacios José
Abstract excerpt
PURPOSE: Basal-like phenotype tumors are frequently found among BRCA1 germ-line mutated breast carcinomas. They are biologically aggressive and have a tendency towards visceral metastasis when untreated. Nevertheless, it has been suggested that they respond to chemotherapy better than other types of tumors. Fascin expression has been associated with lung metastasis in breast cancer. The aim of this study was to...
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