Article
Prognostic significance of basal-like phenotype and fascin expression in node-negative invasive breast carcinomas.
Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Mar 2006
Rodríguez-Pinilla Socorro María, Sarrió David, Honrado Emiliano, Hardisson David, Calero Francisco, Benitez Javier, Palacios José
Abstract excerpt
PURPOSE: Basal-like phenotype tumors are frequently found among BRCA1 germ-line mutated breast carcinomas. They are biologically aggressive and have a tendency towards visceral metastasis when untreated. Nevertheless, it has been suggested that they respond to chemotherapy better than other types...
Topics
- Actins
- Adult
- Aged
- Aged, 80 and over
- BRCA1 Protein
- BRCA2 Protein
- Breast Neoplasms
- Carrier Proteins
- ErbB Receptors
- Female
- Humans
- Keratin-5
- Keratin-6
- Keratins
- Lymph Nodes
- Microfilament Proteins
- Middle Aged
- Neoplasm Invasiveness