Article
Lympho-vascular invasion in BRCA related breast cancer compared to sporadic controls.
BMC cancer - 16 Apr 2010
Heerma van Voss Marise R, van der Groep Petra, Bart Jos, van der Wall Elsken, van Diest Paul J
Abstract excerpt
BACKGROUND: Germline mutations in the BRCA1 gene predispose to the development of breast cancer, exhibiting a specific histological phenotype. Identification of possible hallmarks of these tumors is important for selecting patients for genetic screening and provides inside in carcinogenetic pathways.Since BRCA1-associated breast cancers have pushing borders that prevent them from easily reaching vessels and are...
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