Article
Caveolin-1 promotes mammary tumorigenesis: mutational profile of the Kashmiri population.
Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2010
Syeed Nidda, Husain Syed Akhtar, Abdullah Safiya, Sameer A Syed, Chowdri Nissar A, Nanda Mahoor S, Siddiqi Mushtaq A
Abstract excerpt
BACKGROUND: The role of caveolae and the caveolin proteins in cancer has been the subject of extensive research. It has been suggested that caveolin-1 (Cav-1) may contribute to certain steps of carcinogenesis. In the present study we focused on its potential clinical relevance in mammary malignancies. METHODS: We investigated 130 breast cancer samples along with adjacent normal tissues using allele specific PCR...
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