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Article

Haplotypic structure across the I kappa B alpha gene (NFKBIA) and association with multiple myeloma.

Cancer letters - 8 Feb 2007

Spink Charlotte F, Gray Lisa C, Davies Faith E, Morgan Gareth J, Bidwell Jeffrey L

Abstract excerpt

Polymorphisms in NFKBIA may be important in pre-disposition to and outcome after treatment, of multiple myeloma (MM). The NFKBIA gene product, IkappaBalpha, binds to NF-kappaB preventing its activation and is important in mediating resistance to apoptosis in B-cell lymphoproliferative diseases. This study investigates eight polymorphisms across the NFKBIA gene in large patient and control populations. Significant...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16540234
DOI: 10.1016/j.canlet.2006.02.001

Genes

NFKBIA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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