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Article

A functional polymorphism in the promoter region of the IL1B gene is associated with risk of multiple myeloma.

British journal of haematology - 1 Aug 2012

Vangsted Annette J, Nielsen Kaspar R, Klausen Tobias W, Haukaas Einar, Tjønneland Anne, Vogel Ulla

Abstract excerpt

The cytokine interleukin-1β (IL1B) is important for anti-tumour immune response. Genetic variation may modify the expression of IL1B and thereby influence the risk of disease. We investigated genetic variations with functional importance in the IL1B and NFKB1 genes in 348 population-based samples of multiple myeloma (MM) and a random sample of 1700 individuals. Carriers of the variant T-allele IL1B C-3737T and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 22540426
DOI: 10.1111/j.1365-2141.2012.09141.x

Genes

NFKB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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