Article
bFGF Polymorphism Is Associated with Disease Progression and Response to Chemotherapy in Multiple Myeloma Patients.
Anticancer research - 1 Apr 2017
Wróbel Tomasz, Butrym Aleksandra, Łacina Piotr, Rybka Justyna, Gębura Katarzyna, Mazur Grzegorz, Bogunia-Kubik Katarzyna
Abstract excerpt
BACKGROUND/AIM: Vascular endothelial growth factor (VEGF) and basic fibroblast growth factor (bFGF) play an important role in the initiation of angiogenesis. We aimed to assess whether polymorphisms within the genes coding for these angiogenic activators (VEGF (rs3025039;C>T) and bFGF (rs308395;G>C)) contribute to susceptibility and/or progression in multiple myeloma patients (MM) and to chemotherapy. PATIENTS...
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