Article
Comparison of regulatory sequences and enhancer activities of SV40 variants isolated from patients with neurological diseases.
Virus research - 1 May 1991
Martin J D, Li P N
Abstract excerpt
The genomic regulatory regions of human isolates of SV40 were compared by nucleotide sequencing and by biological assays of their transcriptional enhancers. SVAST is a defective genome and SVMEN an infectious genome molecularly cloned from human astrocytoma and meningioma, respectively (Krieg and Scherer, 1984). SVPML is an isolate from a case of progressive multifocal leukoencephalopathy (Weiner et al., 1972)....
Topics
- DNA, Viral
- Enhancer Elements, Genetic
- Genes, Regulator
- Genes, Viral
- Genetic Variation
- Humans
- Nervous System Diseases
- Simian virus 40
