Article
Functional comparison of PML-type and archetype strains of JC virus.
Journal of virology - 1 Mar 1996
Sock E, Renner K, Feist D, Leger H, Wegner M
Abstract excerpt
Isolates of the human polyomavirus JC can be grouped as either PML-type or archetype strains primarily on the basis of divergence in their regulatory regions. Only PML-type viruses have so far been found to be associated with the human demyelinating disease progressive multifocal leukoencephalopa...
Topics
- Antigens, Polyomavirus Transforming
- Base Sequence
- Cell Line
- DNA Replication
- DNA, Viral
- DNA-Binding Proteins
- Gene Expression Regulation, Viral
- Genetic Variation
- Humans
- JC Virus
- Leukoencephalopathy, Progressive Multifocal
- Molecular Sequence Data
- Neuroglia
- Octamer Transcription Factor-6
- Species Specificity
- Transcription Factors
- Tumor Virus Infections
- Virus Replication