Article
Natural simian virus 40 strains are present in human choroid plexus and ependymoma tumors.
Virology - 1 Oct 1995
Lednicky J A, Garcea R L, Bergsagel D J, Butel J S
Abstract excerpt
Simian virus 40 (SV40) sequences for large tumor antigen (T-ag) were recently detected in a significant fraction of certain human brain tumors of early childhood (Bergsagel et al., N. Engl. J. Med. 326, 988-993, 1992). In the current study, we sought to determine whether authentic SV40 was present in the choroid plexus and ependymoma tumors previously examined. Polymerase chain reaction and DNA sequence analysis...
Topics
- Amino Acid Sequence
- Animals
- Antigens, Polyomavirus Transforming
- Base Sequence
- Capsid
- Cell Line
- Child
- Child, Preschool
- Choroid Plexus Neoplasms
- Cytopathogenic Effect, Viral
- DNA, Viral
