Article
Dynamics of the nucleoprotein structure of simian virus 40 regulatory region during viral development.
Journal of molecular biology - 13 May 1994
Oppenheim A, Siani M, Sandalon Z, Mengeritsky G
Abstract excerpt
The regulatory region of SV40 is composed of multiple elements, including the origin of replication (ori), the encapsidation signal (ses) and the enhancer. Here, the structure of the chromatin and nucleoprotein complexes in a region encompassing ses and part of the enhancer was investigated in detail by in situ probing with DNase I. We have used a model experimental system based on plasmids which carry parts of...
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