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Article

SV40 DNA in human osteosarcomas shows sequence variation among T-antigen genes.

International journal of cancer - 4 Sept 1997

Lednicky J A, Stewart A R, Jenkins J J, Finegold M J, Butel J S

Abstract excerpt

Authentic simian virus 40 (SV40) has been detected in association with human choroid plexus and ependymoma tumors, and SV40-like DNA sequences have been found in some human osteosarcomas. We report here an analysis of human osteosarcoma samples for the presence of SV40 DNA using PCR and primers directed at 4 distinct sites of the SV40 genome, coupled with sequence analysis. Authentic SV40 DNA sequences were...

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PMID: 9311596
DOI: 10.1002/(sici)1097-0215(19970904)72:5<791::aid-ijc15>3.0.co;2-c

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