Brain and kidney of progressive multifocal leukoencephalopathy patients contain identical rearrangements of the JC virus promoter/enhancer.

doi:10.1002/jmv.1890440315

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Article

Brain and kidney of progressive multifocal leukoencephalopathy patients contain identical rearrangements of the JC virus promoter/enhancer.

Journal of medical virology - 1 Nov 1994

Ault G S, Stoner G L

Abstract excerpt

The kidneys of six progressive multifocal leukoencephalopathy (PML) patients were examined by PCR amplification for the presence of JC virus. Amplification of three different areas of the viral genome from multiple samples of each kidney revealed three that were positive for the virus. The use of...

Topics

Base Sequence
Brain
DNA, Viral
Deoxyribonucleases, Type II Site-Specific
Enhancer Elements, Genetic
Gene Rearrangement
Genotype
Humans
JC Virus
Kidney
Leukoencephalopathy, Progressive Multifocal
Molecular Sequence Data
Polymerase Chain Reaction
Promoter Regions, Genetic
Regulatory Sequences, Nucleic Acid
Sequence Analysis, DNA

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Identifiers

PMID: 7852974
DOI: 10.1002/jmv.1890440315

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7852974-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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