Article
Role of the human T-cell leukemia virus type 1 PTAP motif in Gag targeting and particle release.
Journal of virology - 1 Apr 2006
Dorweiler Irene J, Ruone Susan J, Wang Huating, Burry Richard W, Mansky Louis M
Abstract excerpt
Human T-cell leukemia virus type 1 (HTLV-1) Gag is targeted to the plasma membrane for particle assembly and release. How HTLV-1 Gag targeting occurs is not well understood. The PPPY and PTAP motifs were previously shown to be involved in HTLV-1 particle release with PTAP playing a more subtle role in virus budding. These L domains function through the interaction with host cellular proteins normally involved in...
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