Article
Late assembly motifs of human T-cell leukemia virus type 1 and their relative roles in particle release.
Journal of virology - 1 Jun 2004
Heidecker Gisela, Lloyd Patricia A, Fox Kristi, Nagashima Kunio, Derse David
Abstract excerpt
Three late assembly domain consensus motifs, namely PTAP, PPPY, and LYPXL, have been identified in different retroviruses. They have been shown to interact with the cellular proteins TSG101, Nedd4, and AP2 or AIP, respectively. Human T-cell leukemia virus type 1 (HTLV-1) has a PPPY and a PTAP motif, separated by two amino acids, located at the end of MA, but only the PPPY motif is conserved in the deltaretrovirus...
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