Article
Equine infectious anemia virus utilizes host vesicular protein sorting machinery during particle release.
Journal of virology - 1 Aug 2003
Tanzi Giancarlo O, Piefer Andrew J, Bates Paul
Abstract excerpt
A final step in retrovirus assembly, particle release from the cell, is modulated by a small motif in the Gag protein known as a late domain. Recently, human immunodeficiency virus type 1 (HIV-1) and Moloney murine leukemia virus (M-MuLV) were shown to require components of the cellular vacuolar protein sorting (VPS) machinery for efficient viral release. HIV-1 interacts with the VPS pathway via an association of...
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