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Article

Evidence that productive human immunodeficiency virus type 1 assembly can occur in an intracellular compartment.

Journal of virology - 1 Jun 2009

Joshi Anjali, Ablan Sherimay D, Soheilian Ferri, Nagashima Kunio, Freed Eric O

Abstract excerpt

Human immunodeficiency virus type 1 (HIV-1) assembly occurs predominantly at the plasma membrane of infected cells. The targeting of assembly to intracellular compartments such as multivesicular bodies (MVBs) generally leads to a significant reduction in virus release efficiency, suggesting that MVBs are a nonproductive site for HIV-1 assembly. In the current study, we make use of an HIV-1 Gag-matrix mutant,...

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Topics

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Share to Antigens, CD
Share to Endocytosis
Share to gag Gene Products, Human Immunodeficiency Virus

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Intracellular Space

Share to Microscopy, Electron

Share to Platelet Membrane Glycoproteins

Share to T-Lymphocytes

Share to Virus Assembly

Source

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Identifiers

PMID: 19297499
DOI: 10.1128/JVI.00109-09
PMCID: PMC2681934

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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