Article
Identification of base pairs in single-nucleotide polymorphisms by MutS protein-mediated capillary electrophoresis.
Analytical chemistry - 15 Mar 2006
Drabovich Andrei P, Krylov Sergey N
Abstract excerpt
Single-nucleotide polymorphisms (SNPs) are widespread genomic variations, which are associated with serious health disorders and drug resistance. Multiple clinical applications and studies of global population genetics require fast and informative analysis of SNPs. Most of conventional methods sense the presence of the SNP but cannot identify the base pair in it. Here we report simple identification of base pairs...
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