Article
Integrated platform for detection of DNA sequence variants using capillary array electrophoresis.
Electrophoresis - 1 May 2002
Li Qingbo, Liu Zhaowei, Monroe Heidi, Culiat Cymbeline T
Abstract excerpt
We have developed a highly versatile platform that performs temperature gradient capillary electrophoresis (TGCE) for mutation/single-nucleotide polymorphism (SNP) detection, sequencing and mutation/SNP genotyping for identification of sequence variants on an automated 24-, 96- or 192-capillary array instrument. In the first mode, multiple DNA samples consisting of homoduplexes and heteroduplexes are separated by...
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