Article
Detection of point mutation and insertion mutations in DNA using a quartz crystal microbalance and MutS, a mismatch binding protein.
Analytical chemistry - 15 Jan 2004
Su Xiaodi, Robelek Rudolf, Wu Yingju, Wang Guangyu, Knoll Wolfgang
Abstract excerpt
MutS protein is a mismatch binding protein that recognizes mispaired and unpaired base(s) in DNA. In this study, we incorporate the MutS protein-based mutation recognition into quartz crystal microbalance (QCM) measurements for DNA single-base substitution mutation and 1-4 base(s) insertion (or d...
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