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Article

The mouse lymphoma assay.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2012

Lloyd Melvyn, Kidd Darren

Abstract excerpt

The mouse lymphoma TK assay (MLA) is part of an in vitro battery of tests designed to predict risk assessment prior to in vivo testing. The test has the potential to detect mutagenic and clastogenic events at the thymidine kinase (tk) locus of L5178Y mouse lymphoma tk ( +/- ) cells by measuring resistance to the lethal nucleoside analogue triflurothymidine (TFT). Cells...

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Identifiers

PMID: 22147567
DOI: 10.1007/978-1-61779-421-6_3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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