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Article

Induction of mutagenesis and transformation in BALB/c-3T3 clone A31-1 cells by diverse chemical carcinogens.

Environmental and molecular mutagenesis - 1 Jan 1990

Lubet R A, Kouri R E, Curren R A, Putman D L, Schechtman L M

Abstract excerpt

BALB/c-3T3 cells were employed to examine the genotoxic potential of a variety of known chemical carcinogens. BALB/c-3T3 cells displayed a dose-dependent transformation response to a variety of carcinogens (polycyclic hydrocarbons, methylating agents, ethylating agents, aflatoxin B1 [AFB1], and 4-nitroquinoline-N-oxide [4-NQO]). When the ability of these compounds to induce mutagenesis to resistance to the...

Topics

Alkylating Agents
Animals
Azacitidine
Carcinogens
Cell Line
Cell Transformation, Neoplastic
Mice
Mice, Inbred BALB C
Mutagenicity Tests
Mutation
Polycyclic Compounds

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Identifiers

PMID: 1695571
DOI: 10.1002/em.2850160103

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1695571-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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