Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The use of random controls in genetic association studies.

Human heredity - 1 Jan 2006

Garner Chad

Abstract excerpt

BACKGROUND: The optimal control sample would be ethnically-matched and at minimal risk of developing the disease. Alternatively, one could collect random individuals from the population or select individuals to reduce the number of at-risk individuals in the sample. The effect of randomly selected individuals in a control sample on the statistical power and the odds ratio estimate was investigated. METHODS: Case...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Case-Control Studies
Share to Gene Frequency
Share to Genetic Markers

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetics, Population

Share to Models, Statistical

Share to Odds Ratio

Share to Polymorphism, Genetic

Source

Identifiers

PMID: 16534212
DOI: 10.1159/000091833

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The use of random controls in genetic association studies.PMID 16534212Read ↗

Design of case-controls studies with unscreened controls.Semantic proximity Read ↗

Examining the rare disease assumption used to justify HWE testing with control samples.Semantic proximity Read ↗

Using Alternative Definitions of Controls to Increase Statistical Power in GWASSemantic proximity Read ↗

Using Alternative Definitions of Controls to Increase Statistical Power in GWAS.Semantic proximity Read ↗

Interval estimation of genetic susceptibility for retrospective case-control studies.Semantic proximity Read ↗

Pathogen exposure misclassification can bias association signals in GWAS of infectious diseases when using population-based common controlsSemantic proximity Read ↗

Biased tests of association: comparisons of allele frequencies when departing from Hardy-Weinberg proportions.Semantic proximity Read ↗

Using both cases and controls for testing hardy-weinberg proportions in a genetic association study.Semantic proximity Read ↗

Minimum sample size estimation to detect gene-environment interaction in case-control designs.Semantic proximity Read ↗

Sampling GWAS subjects from risk populations.Semantic proximity Read ↗

Power and sample size calculations in the presence of phenotype errors for case/control genetic association studies.Semantic proximity Read ↗

Allowing for genotyping error in analysis of unmatched case-control studies.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.