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Article

Sampling GWAS subjects from risk populations.

Genetic epidemiology - 1 Apr 2011

Oexle Konrad, Meitinger Thomas

Abstract excerpt

Power, i.e. sample size, is a crucial issue in genome-wide association studies (GWAS) on disorders generated by a multitude of weak genetic effects. Here, we examine the influence of sampling cases and/or controls from populations that are subjected to an external risk factor (such as smoking or nutritional factors). We use an additive threshold model and derive the necessary sample size as function of the...

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PMID: 21328614
DOI: 10.1002/gepi.20562

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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