Article
Using both cases and controls for testing hardy-weinberg proportions in a genetic association study.
Human heredity - 1 Jan 2010
Wang Jian, Shete Sanjay
Abstract excerpt
OBJECTIVES: Assessment of the Hardy-Weinberg proportion (HWP) in controls has been widely used as a quality control measure in case-control association studies. However, when the disease being studied is common, controls might not represent the general population, which could result in inaccurate...
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