Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Modification of the wobble uridine in bacterial and mitochondrial tRNAs reading NNA/NNG triplets of 2-codon boxes

2 Dec 2014

Abstract excerpt

Posttranscriptional modification of the uridine located at the wobble position (U34) of tRNAs is crucial for optimization of translation. Defects in the U34 modification of mitochondrial-tRNAs are associated with a group of rare diseases collectively characterized by the impairment of the oxidative phosphorylation system. Retrograde signaling pathways from mitochondria to nucleus are involved in the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to ATP Synthase and ATPases Research
Share to Peptidase Inhibition and Analysis
Share to RNA modifications and cancer

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 25607529
DOI: 10.4161/15476286.2014.992269

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Modification of the wobble uridine in bacterial and mitochondrial tRNAs reading NNA/NNG triplets of 2-codon boxesPMID 25607529Read ↗

[Nucleotide modification of mitochondrial tRNA and mitochondrial diseases].Semantic proximity Read ↗

Human mitochondrial diseases associated with tRNA wobble modification deficiency.Semantic proximity Read ↗

Lost in Translation: Defects in Transfer RNA Modifications and Neurological DisordersSemantic proximity Read ↗

Mitochondrial tRNA modifications: functions, diseases caused by their loss, and treatment strategies.Semantic proximity Read ↗

Methylated nucleosides in tRNA and tRNA methyltransferasesSemantic proximity Read ↗

Charging the code — tRNA modification complexesSemantic proximity Read ↗

7-Methylguanosine Modifications in tRNASemantic proximity Read ↗

Queuosine modification of tRNA: its divergent role in cellular machinerySemantic proximity Read ↗

tRNA modifications: greasing the wheels of translation and beyondSemantic proximity Read ↗

Human TRUB1 is a highly conserved pseudouridine synthase responsible for the formation of Ψ55 in mitochondrial tRNAAsn, tRNAGln, tRNAGlu and tRNAProSemantic proximity Read ↗

Biosynthesis and function of posttranscriptional modifications of transfer RNAs.Semantic proximity Read ↗

Research Advances on Deafness Genes Associated with Mitochondrial tRNA-37 Modifications.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.