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Article

Non-infectious fluorimetric assay for phenotyping of drug-resistant HIV proteinase mutants.

Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology - 1 May 2006

Majerová-Uhlíková Tat'ána, Dantuma Nico P, Lindsten Kristina, Masucci Maria G, Konvalinka Jan

Abstract excerpt

BACKGROUND: The introduction of HIV proteinase inhibitors (PIs) as anti-AIDS drugs resulted in decreased mortality and prolonged life expectancy of HIV-positive patients. However, rapid selection of drug-resistant HIV variants is a common complication in patients undergoing highly active anti-retroviral therapy (HAART). Thus, monitoring of clinical resistance development is indispensable for rational...

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Identifiers

PMID: 16527535
DOI: 10.1016/j.jcv.2006.01.014

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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