Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Assessment of the susceptibility of mutant HIV-1 to antiviral agents.

Journal of virological methods - 1 May 2010

Wang Ying-Jie, McKenna Philip M, Hrin Renee, Felock Peter, Lu Meiqing, Jones Kristen G, Coburn Craig A, Grobler Jay A, Hazuda Daria J, Miller Michael D, Lai Ming-Tain

Abstract excerpt

Traditional phenotypic assays used to assess the susceptibility of mutant human immunodeficiency virus type-1 (HIV-1) obtained from infected patients or from resistance selection to antiviral agents in cell culture are rather tedious and time consuming. To improve the efficiency of this process, a novel method was developed in which mutant viruses are captured with magnetic nano-beads and used to infect gag-GFP...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anti-HIV Agents
Share to Biological Assay

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Drug Resistance, Multiple, Viral

Share to Drug Resistance, Viral

Share to gag Gene Products, Human Immunodeficiency Virus

Share to Green Fluorescent Proteins

Share to Microspheres

Share to Mutagenesis, Site-Directed

Source

Identifiers

PMID: 20153375
DOI: 10.1016/j.jviromet.2010.02.002

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Assessment of the susceptibility of mutant HIV-1 to antiviral agents.PMID 20153375Read ↗

A simple and cost-saving phenotypic drug susceptibility testing of HIV-1.Semantic proximity Read ↗

Novel single-cell-level phenotypic assay for residual drug susceptibility and reduced replication capacity of drug-resistant human immunodeficiency virus type 1.Semantic proximity Read ↗

Efficient identification of human immunodeficiency virus type 1 mutants resistant to a protease inhibitor by using a random mutant library.Semantic proximity Read ↗

A recombinant retroviral system for rapid in vivo analysis of human immunodeficiency virus type 1 susceptibility to reverse transcriptase inhibitorsSemantic proximity Read ↗

A novel phenotypic drug susceptibility assay for human immunodeficiency virus type 1.Semantic proximity Read ↗

Non-infectious fluorimetric assay for phenotyping of drug-resistant HIV proteinase mutants.Semantic proximity Read ↗

Phenotypic analysis of the sensitivity of HIV-1 to inhibitors of the reverse transcriptase, protease, and integrase using a self-inactivating virus vector system.Semantic proximity Read ↗

Rapid and simple phenotypic assay for drug susceptibility of human immunodeficiency virus type 1 using CCR5-expressing HeLa/CD4(+) cell clone 1-10 (MAGIC-5).Semantic proximity Read ↗

Phenotypic changes in drug susceptibility associated with failure of human immunodeficiency virus type 1 (HIV-1) triple combination therapy.Semantic proximity Read ↗

A single-loop recombinant pseudotyped-virus-based assay to detect HIV-1 phenotypic resistance.Semantic proximity Read ↗

Selection and analysis of HIV-1 integrase strand transfer inhibitor resistant mutant viruses.Semantic proximity Read ↗

Rapid genetic selection of inhibitor-resistant protease mutants: clinically relevant and novel mutants of the HIV protease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.