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Article

Selective loss of resistant alleles at p15INK4B and p16INK4A genes in chemically-induced rat tongue cancers.

Oral oncology - 1 Aug 2006

Ogawa Kotaro, Tanuma Jun-ichi, Hirano Masato, Hirayama Yoshikazu, Semba Ichiro, Shisa Hayase, Kitano Motoo

Abstract excerpt

We previously reported that susceptibility to 4-nitroquinoline 1-oxide (4NQO)-induced tongue cancer in Dark-Agouti (DA) and Wistar/Furth (WF) rats was determined by a number of quantitative trait loci. In this article, we further scrutinized one of the quantitative trait loci at a suggestive level on rat chromosome 5. Analyzing a DNA panel of 130 (DAxWF) F2 rats treated with 4NQO showed a quantitative trait loci,...

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Identifiers

PMID: 16527513
DOI: 10.1016/j.oraloncology.2005.11.011

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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