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Article

Pthlh, a promising cancer modifier gene in rat tongue carcinogenesis.

Oncology reports - 1 Jan 2014

Suwa Hirohiko, Hirano Masato, Kawarada Kouji, Nagayama Motohiko, Ehara Michiko, Muraki Tomonari, Shisa Hayase, Sugiyama Aiko, Sugimoto Masahiro, Hiai Hiroshi, Kitano Motoo, Tanuma Jun-Ichi

Abstract excerpt

Susceptibly to the induction of rat tongue cancer (TC) by oral 4-nitroquinoline 1-oxide (4NQO) exposure is a polygenic trait. Among several quantitative trait loci identified by crosses between TC-susceptible Dark Agouti (DA) rats and TC-resistant Wistar-Furth (WF) rats, we focused on tongue cancer susceptibility locus (Tcas3) of chromosome 4. We examined tongue carcinogenesis in the reciprocal congenic strains...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Parathyroid Hormone-Related Protein

Share to Rats, Inbred F344

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Source

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Identifiers

PMID: 24253735
DOI: 10.3892/or.2013.2859
PMCID: PMC3868494

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