Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Five quantitative trait loci affecting 4-nitroquinoline 1-oxide-induced tongue cancer in the rat.

Japanese journal of cancer research : Gann - 1 Jun 2001

Tanuma J I, Fujii K, Hirano M, Matsuuchi H, Shisa H, Hiai H, Kitano M

Abstract excerpt

In our previous study, Dark-Agouti (DA) rats were found to be highly susceptible to 4-nitroquinoline 1-oxide (4NQO)-induced tongue carcinoma (TC), whereas Wistar / Furth (WF) rats were barely susceptible. Interval mapping analysis of reciprocal backcross rats showed two quantitative trait loci (QTL) on rat chromosomes (RNO) 1 and 19. In the present study, a composite interval mapping analysis was applied to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to 4-Nitroquinoline-1-oxide
Share to Carcinogens

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genome

Share to Homozygote

Share to Lod Score

Share to Quantitative Trait, Heritable

Share to Tongue Neoplasms

Source

Open in PubMed Open full text

Identifiers

PMID: 11429048
DOI: 10.1111/j.1349-7006.2001.tb01138.x
PMCID: PMC5926756

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Five quantitative trait loci affecting 4-nitroquinoline 1-oxide-induced tongue cancer in the rat.PMID 11429048Read ↗

Genetic predisposition to 4NQO-induced tongue carcinogenesis in the rat.Semantic proximity Read ↗

A speed congenic rat strain bearing the tongue cancer susceptibility locus Tscc1 from Dark-Agouti rats.Semantic proximity Read ↗

Host genes controlling the susceptibility and resistance to squamous cell carcinoma of the tongue in a rat model.Semantic proximity Read ↗

Pthlh, a promising cancer modifier gene in rat tongue carcinogenesis.Semantic proximity Read ↗

Selective loss of resistant alleles at p15INK4B and p16INK4A genes in chemically-induced rat tongue cancers.Semantic proximity Read ↗

Carcinogenesis modifier loci in rat tongue are subject to frequent loss of heterozygosity.Semantic proximity Read ↗

Frequent mutation of p16(CDKN2A) exon 1 during rat tongue carcinogenesis induced by 4-nitroquinoline-1-oxide.Semantic proximity Read ↗

p53 Transgenic mice are highly susceptible to 4-nitroquinoline-1-oxide-induced oral cancer.Semantic proximity Read ↗

No mutations found in exon 2 of gene p16CDKN2A during rat tongue carcinogenesis induced by 4-nitroquinoline-1-oxide.Semantic proximity Read ↗

The role of the TP53 gene during rat tongue carcinogenesis induced by 4-nitroquinoline 1-oxide.Semantic proximity Read ↗

Enhancement of tongue carcinogenesis in Hras128 transgenic rats treated with 4-nitroquinoline 1-oxide.Semantic proximity Read ↗

Identification and characterization of a highly metastatic epithelial cancer cell line from rat tongue cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.