Advances in molecular genetics of panic disorder.

doi:10.1038/mp.2009.145

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Article

Advances in molecular genetics of panic disorder.

Molecular psychiatry - 1 Jul 2010

Maron E, Hettema J M, Shlik J

Abstract excerpt

The molecular genetic research on panic disorder (PD) has grown tremendously in the past decade. Although the data from twin and family studies suggest an involvement of genetic factors in the familial transmission of PD with the heritability estimate near 40%, the genetic substrate underlying panicogenesis is not yet understood. The linkage studies so far have suggested that chromosomal regions 13q, 14q, 22q,...

Topics

Catechol O-Methyltransferase
Gene Expression
Genetic Linkage
Genetic Predisposition to Disease
Genome-Wide Association Study
Humans
Models, Biological
Models, Psychological
Panic Disorder
Polymorphism, Genetic

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Open in PubMed

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PMID: 20048750
DOI: 10.1038/mp.2009.145

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