Repression and activation of promoter-bound RNA polymerase activity by Gal repressor.

doi:10.1006/jmbi.1997.1221

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Article

Repression and activation of promoter-bound RNA polymerase activity by Gal repressor.

Journal of molecular biology - 26 Sept 1997

Choy H E, Hanger R R, Aki T, Mahoney M, Murakami K, Ishihama A, Adhya S

Abstract excerpt

By binding to the DNA site OE at position -60.5 in the gal operon, the GalR protein activates transcription from the P2 promoter located on the opposite face of DNA (position -5) and represses transcription from the P1 promoter located on the same face (position +1). GalR increases RNA polymerase...

Topics

Binding Sites
DNA-Directed RNA Polymerases
Escherichia coli
Escherichia coli Proteins
Galactose
Gene Expression Regulation
Models, Genetic
Mutation
Operon
Promoter Regions, Genetic
Protein Binding
Repressor Proteins
Transcription, Genetic

Source

Open in PubMed

Identifiers

PMID: 9325090
DOI: 10.1006/jmbi.1997.1221

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9325090-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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