Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Repression and activation of promoter-bound RNA polymerase activity by Gal repressor.

Journal of molecular biology - 26 Sept 1997

Choy H E, Hanger R R, Aki T, Mahoney M, Murakami K, Ishihama A, Adhya S

Abstract excerpt

By binding to the DNA site OE at position -60.5 in the gal operon, the GalR protein activates transcription from the P2 promoter located on the opposite face of DNA (position -5) and represses transcription from the P1 promoter located on the same face (position +1). GalR increases RNA polymerase binding at P2 and inhibits isomerization at P1 by forming a GalR-DNA-RNA polymerase ternary complex in each case. The...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Binding Sites
Share to Escherichia coli
Share to Escherichia coli Proteins

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Gene Expression Regulation

Share to Models, Genetic

Share to Mutation

Share to Promoter Regions, Genetic

Share to Transcription, Genetic

Source

Identifiers

PMID: 9325090
DOI: 10.1006/jmbi.1997.1221

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Repression and activation of promoter-bound RNA polymerase activity by Gal repressor.PMID 9325090Read ↗

Three-stage regulation of the amphibolic gal operon: from repressosome to GalR-free DNA.Semantic proximity Read ↗

Operator-bound GalR dimers close DNA loops by direct interaction: tetramerization and inducer binding.Semantic proximity Read ↗

Differential role of base pairs on gal promoters strength.Semantic proximity Read ↗

In vitro repression of the gal promoters by GalR and HU depends on the proper helical phasing of the two operators.Semantic proximity Read ↗

Histone-like protein HU as a specific transcriptional regulator: co-factor role in repression of gal transcription by GAL repressor.Semantic proximity Read ↗

The role of an upstream promoter interaction in initiation of bacterial transcription.Semantic proximity Read ↗

On the role of the Escherichia coli RNA polymerase sigma 70 region 4.2 and alpha-subunit C-terminal domains in promoter complex formation on the extended -10 galP1 promoter.Semantic proximity Read ↗

The non-inducible nature of super-repressors of the gal operon in Escherichia coli.Semantic proximity Read ↗

DNA sequence requirements for the activation of 434 P(RM) transcription by 434 repressor.Semantic proximity Read ↗

A mutant RNA polymerase that forms unusual open promoter complexes.Semantic proximity Read ↗

Specific contacts of the -35 region of the galP1 promoter by RNA polymerase inhibit GalR-mediated DNA looping repression.Semantic proximity Read ↗

A dual promoter system regulating λ DNA replication initiation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.