Article
Specific contacts of the -35 region of the galP1 promoter by RNA polymerase inhibit GalR-mediated DNA looping repression.
Nucleic acids research - 1 Nov 2012
Csiszovszki Zsolt, Lewis Dale E A, Le Phuoc, Sneppen Kim, Semsey Szabolcs
Abstract excerpt
The P1 promoter of the galactose operon in Escherichia coli is one of the best studied examples of 'extended -10' promoters. Recognition of the P1 promoter does not require specific contacts between RNA polymerase and its poor -35 element. To investigate whether specific recognition of the -35 element would affect the regulation of P1 by GalR, we mutagenized the -35 element of P1, isolated variants of the -35...
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