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Article

Mechanism of sulfotransferase pharmacogenetics in altered xenobiotic metabolism.

Expert opinion on drug metabolism & toxicology - 1 Jul 2015

Chen Bo-Han, Wang Chen-Chu, Hou You-Hua, Mao Yi-Chih, Yang Yuh-Shyong

Abstract excerpt

INTRODUCTION: Cytosolic sulfotransferases (SULTs), one of the vital enzymes of detoxication, catalyze the sulfation of native and exogenous hydrophobic molecules. Xenobiotic accumulation can induce a variety of diseases, including cancers. Sulfation facilitates the solubilization and removal of xenobiotics. However, sulfation may activate the pharmacological activities of xenobiotics. AREAS COVERED: The purpose...

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Identifiers

PMID: 26073579
DOI: 10.1517/17425255.2015.1045486

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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