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Article

Antigenomic delta ribozyme variants with mutations in the catalytic core obtained by the in vitro selection method.

Nucleic acids research - 1 Jan 2006

Łegiewicz Michał, Wichłacz Agnieszka, Brzezicha Bartosz, Ciesiołka Jerzy

Abstract excerpt

We have used the in vitro selection method to search for catalytically active variants of the antigenomic delta ribozyme with mutations in the regions that constitute the ribozyme active site: L3, J1/4 and J4/2. In the initial combinatorial library 16 nt positions were randomized and the library...

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Identifiers

PMID: 16513845
DOI: 10.1093/nar/gkl018
PMCID: PMC1388270

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16513845-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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