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Article

Ribozyme activity in the genomic and antigenomic RNA strands of hepatitis delta virus.

Cellular and molecular life sciences : CMLS - 1 Jan 2002

Wadkins T S, Been M D

Abstract excerpt

In the hepatitis delta virus, ribozymes are encoded in both the genomic strand RNA and its complement, the antigenomic strand. The two ribozymes are similar in sequence and structure, are most active in the presence of divalent cation and catalyze RNA cleavage reactions which generate a 5'-hydroxyl group and a 2',3'-cyclic phosphate group. Recent progress has been made in understanding the catalytic mechanism....

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Share to Base Sequence
Share to Genome, Viral
Share to Hepatitis Delta Virus

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Nucleic Acid Conformation

Share to Polyadenylation

Share to RNA, Catalytic

Share to RNA, Viral

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Source

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Identifiers

PMID: 11846024
DOI: 10.1007/s00018-002-8409-7
PMCID: PMC11337493

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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