Article
Characterization of the trans Watson-Crick GU base pair located in the catalytic core of the antigenomic HDV ribozyme.
PloS one - 1 Jan 2012
Lévesque Dominique, Reymond Cédric, Perreault Jean-Pierre
Abstract excerpt
The HDV ribozyme's folding pathway is, by far, the most complex folding pathway elucidated to date for a small ribozyme. It includes 6 different steps that have been shown to occur before the chemical cleavage. It is likely that other steps remain to be discovered. One of the most critical of these unknown steps is the formation of the trans Watson-Crick GU base pair within loop III. The U(23) and G(28)...
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