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Article

Epigenetic alterations in RASSF1A in human aberrant crypt foci.

Carcinogenesis - 1 Jul 2006

Greenspan Emily J, Jablonski Melissa A, Rajan Thiruchandurai V, Levine Joel, Belinsky Glenn S, Rosenberg Daniel W

Abstract excerpt

CpG island methylation (CIM) is an epigenetic mechanism for transcriptional silencing that occurs at various stages of colon tumorigenesis. CIM has been found in serrated adenomas and hyperplastic polyps. There is also evidence for hypermethylation in aberrant crypt foci (ACF) that are found in r...

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Identifiers

PMID: 16513682
DOI: 10.1093/carcin/bgi373
PMCID: PMC3117759

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16513682-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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