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Article

Extensive DNA methylation in normal colorectal mucosa in hyperplastic polyposis.

Gut - 1 Oct 2006

Minoo P, Baker K, Goswami R, Chong G, Foulkes W D, Ruszkiewicz A R, Barker M, Buchanan D, Young J, Jass J R

Abstract excerpt

BACKGROUND: Hyperplastic polyposis of the colorectum is a precancerous condition that has been linked with DNA methylation. The polyps in this condition have been distinguished from typical small hyperplastic polyps and renamed sessile serrated adenomas. Sessile serrated adenomas also occur sporadically and appear to be indistinguishable from their counterparts in hyperplastic polyposis. AIMS AND METHODS: The...

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Topics

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Share to Adaptor Proteins, Signal Transducing
Share to Colonic Polyps

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to CpG Islands

Share to DNA Methylation

Share to DNA, Neoplasm

Share to MutL Protein Homolog 1

Share to Nuclear Proteins

Share to Proto-Oncogene Proteins B-raf

Source

Open in PubMed Open full text

Identifiers

PMID: 16469793
DOI: 10.1136/gut.2005.082859
PMCID: PMC1856423

Genes

MLH1
BRAF
CHFR
FAS
MGMT
MST1
RASSF1
RASSF2
RASSF5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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