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Article

The emergence of regulated histone proteolysis.

Current opinion in genetics & development - 1 Apr 2006

Gunjan Akash, Paik Johanna, Verreault Alain

Abstract excerpt

Proliferating cells need to synthesize large amounts of histones to rapidly package nascent DNA into nucleosomes. This is a challenging task for cells because changes in rates of DNA synthesis lead to an accumulation of excess histones, which interfere with many aspects of DNA metabolism. In addition, cells need to ensure that histone variants are incorporated at the correct chromosomal location. Recent...

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PMID: 16510276
DOI: 10.1016/j.gde.2006.02.010

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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