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Article

FACT and the reorganized nucleosome.

Molecular bioSystems - 1 Nov 2008

Formosa Tim

Abstract excerpt

FACT is an essential component of the machinery used by eukaryotic cells both to establish and to overcome the nucleosomal barrier to DNA accessibility, and it does so without hydrolyzing ATP. FACT is a transcription elongation factor, but this review stresses additional roles in DNA replication and initiation of transcription. The widely-held model that FACT functions by displacing an H2A-H2B dimer from a...

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Share to Nucleosomes
Share to Transcription, Genetic
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to DNA Replication

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Source

Identifiers

PMID: 18931784
DOI: 10.1039/b812136b

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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